Texas Fertility Center

Egg Donor Cycle Process

Egg donor cycle process for fresh eggs takes approximately a 4-6 weeks

The donor calls with her menstrual flow.

Once all of the screening has been completed and has been found to be normal, you will return to our office to have another exam and sonogram.

The donor starts birth control pill (BCP), antibiotics and folic acid or a prenatal vitamin. A cycle calendar will be mailed to the donor.

You will be instructed to start birth control pills and folic acid or a prenatal vitamin with your menses. A calendar will be made by the donor coordinator to provide you with the anticipated dates of your appointments over the next several weeks. You will also be given an antibiotic to eliminate any potential bacteria that may be in the genitourinary tract.

The donor calls to schedule appointments that are on their calendar and follows calendar for daily instructions.

Your appointments will be scheduled at the physician’s direction and will depend on how you are responding to medication. We will try to work with your schedule as much as possible; however, donors must be somewhat flexible as stimulation of the ovary is unpredictable and the dates on the original cycle calendar may change based on the sonogram and lab results.

The next appointment is called a pre-Lupron sonogram.

At this appointment, the medication will be given to the donor, and she will be given an injection lesson teaching her how to administer the Lupron. Near the end of the pack of birth control pills, you will be scheduled for a sonogram to ensure that you did not develop any ovarian cysts while taking the birth control pills. If this sonogram is normal, you will begin taking a daily subcutaneous injection called Lupron. This medication will continue for about 4 weeks.

The next appointment is called a baseline sonogram.

At this appointment the donor will also receive her FSH medication and be given an injection lesson instructing her how to administer the FSH.
You will finish your birth control pills approximately 4-5 days after starting Lupron. A few days later, you will have a period. You will then come to the office for another sonogram to ensure that you did not develop any cysts as a result of the Lupron. If that sonogram is normal, you will be instructed when to start taking the second injection (FSH).

Monitoring visits

Both the Lupron and the FSH injections will continue for approximately 10-12 days. During that time, you will be monitored with sonograms and blood work approximately every 3 days.

Ovidrel injection.

The donor will be instructed by the on call nurse on the specific time to administer the Ovidrel injection. When the physician determines that your follicles are mature (usually after 10-12 days of FSH medication), you will be instructed to stop both Lupron and FSH. You will then be given a specific time to take Ovidrel, which is a medication that would ordinarily trigger ovulation to occur about 38-40 hours later. In order to prevent ovulation (which would ruin the cycle as the eggs would be lost), the egg retrieval will be scheduled to occur exactly 36 hours after the Ovidrel injection.

The retrieval

The retrieval takes about 20 minutes, and it is followed by a one hour recovery time. Retrievals are performed under IV sedation. You can expect to be groggy and have some uterine cramping for several hours following the procedure. Please note that you will need to have a ride home from the surgery center as you will not be allowed to drive until the anesthesia medication has worn completely off. Post procedure pain medications will be given to you to take at home as needed to minimize discomfort.

Fertility Story


Embryo Clearinghouse


The Department of Health and Human Services, the State of Texas and the American Society for Reproductive Medicine took steps to bring this program to life. TFC supported a bill that would have created a clearinghouse for embryo donation. HB1145 died in committee in April 2015, but it’s important to maintain momentum that began with HB1145.